Patients with Diabetes - Penlac® Nail Lacquer
FOR U.S. RESIDENTS ONLY
Penlac® Nail Lacquer (ciclopirox) Topical Solution, 8%: Safe and on target
About Nail Fungus Treatment with Penlac® For People with Diabetes For Healthcare Professionals
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Patients with Diabetes

Onychomycosis is prevalent in patients with diabetes[9]

  • Patients with diabetes are almost 3 times more likely to get onychomycosis than non-diabetic patients[9]
  • Patients with diabetes and onychomycosis have an increased risk of secondary infection[10-12]*
  • Onychomycosis is associated with a 2- to 4-fold increase in diabetic foot infections[10-12]

Adapted from Robbins and Doyle, et al.[10,12]

The efficacy of Penlac® to reduce the incidence of secondary infections has not been determined.
*The risk of removal of the unattached, infected nail by the health care professional, and trimming by the patients, should be carefully considered before prescribing to patients with a history of insulin-dependent diabetes mellitus or diabetic neuropathy.[1]


Penlac® is indicated in immunocompetent patients with mild to moderate onychomycosis without lunula involvement due to Trichophyton rubrum.
IMPORTANT SAFETY INFORMATION
Penlac®, part of a comprehensive management program, includes regular removal of the unattached, infected nail by a health care professional, especially for patients with diabetes. Clinical data regarding use of systemic antifungals and Penlac® is not available to support concomitant use. Penlac® is well-tolerated: treatment-related side effects were periungual erythema (5%) and nail disorders (2%).

Patients with insulin-dependent diabetes or those with diabetic neuropathy were not included in pivotal clinical trials with Penlac®.
For more information, please see Full Prescribing Information for Penlac®

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